Anthony Lagina
Associate Professor
Anthony Lagina
Office Phone
313-993-2530Office Location
4201 Saint Antoine StreetUHC - 6G
Detroit, MI 48201
Education
M.D.
Wayne State University
1998-2002
Postgraduate Biochemistry Research Training Program
Michigan State University
1997-1998
B.S. Biochemistry (honors)
Michigan State University
1993-1997
Education – Degrees, Licenses, Certifications
M.D., F.A.C.E.P.Residency
Department of Emergency Medicine
Detroit Receiving Hospital/Wayne State University
2002-2005
Accomplishments
Honors/Awards
Emergency Medicine Basic Research Skills (EMBRS) Workshop EMF Award Recipient
2007
WSU Co-Curricular Outreach Award
2002
Michigan State University Biochemistry Undergraduate of the Year Honorable Mention
1997
Michigan State University Dean’s Student Advisory Committee
1996
National Science Foundation Undergraduate Summer Research Fellow
1995
Professional Experience
Service
Wayne State University School of Medicine
Faculty Advisor for the Wilderness Medicine Student Interest Grou[
2005 - present
Professional
Research Committee Research Forum Member
American College of Emergency Physicians
2012 - present
Medical Operations - Search and Rescue Team
Michigan Technical Rescue Operations Team
2005-2008
Scholarly Service
Academic Emergency Medicine Journal Reviewer
2012-present
ILCOR Review Committee - American Health Association
2014-present
ACEP moderator for scientific assembly poster session
2012-present
Teaching
Wayne State University
Undergraduate Students
Bedside and didactic teaching in the emergency department
2005-present
Mentoring and advising for the wilderness medicine student group
2005-present
Medical Students
Beside and didactic teaching in the emergency department
2005-present
Mentoring and advising for the wilderness medicine student group
2005-present
Residents/Fellows
Bedside and didactic teaching for emergency medicine
2005-present
Teaching at other institutions
University of Michigan
Graduate and Medical Students and Faculty
2011-present
Wilderness medicine topics for didactics sessions and workshops
2011-present
Publications
Peer Reviewed Publications
1. Soar J, Callaway CW , Aibiki M, Böttiger BW, Brooks SC, Deakin CD, Donnino MW, Drajer S, Kloeck W, Morley PT, Morrison LJ, Neumar RW, Nicholson TC , Nolan JP, Okada K, O'Neil BJ, Paiva EF, Parr MJ, Wang TL, Witt J; Advanced Life Support Chapter Collaborators.. (2015) Part 4: Advanced life support: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency cardiovascular Care Science with Treatment Recommendations. Resuscitation. 2015 Oct;95:e71-120. doi: 10.1016/j.resuscitation.2015.07.042.
My role was as review collaborator
2. Soar J, Callaway CW , Aibiki M, Böttiger BW, Brooks SC, Deakin CD, Donnino MW, Drajer S, Kloeck W, Morley PT, Morrison LJ, Neumar RW, Nicholson TC , Nolan JP, Okada K, O'Neil BJ, Paiva EF, Parr MJ, Wang TL, Witt J; Advanced Life Support Chapter Collaborators.. (2015) Part 4: Advanced life support: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency cardiovascular Care Science with Treatment Recommendations. Circulation. 2015 Oct 20;132(16 Suppl 1):S84-145. doi: 10.1161/CIR.0000000000000273.
My role was as review collaborator
3. A. Lagina, L. Foster, T. Sanderson, R. Kumar, M. Deogracias, R. Tousignant, J. Wider, J. Sullivan. Combination Therapy with IGF-1 and Hypothermia Synergistically Improves Outcome After Transient Global Brain Ischemia in the Rat. Academic Emergency Medicine, 2013 Apr; 20(4):344-51
My role was as principle investigator
4. Lagina, A. T., Deogracias*, M., Reed*, K., Bazzi*, D., Chepuri*, R., Foster*, L. and Sullivan, J. M. (2012), The “Refrige-a-RAT-or”: An Accurate, Inexpensive, and Anthony Lagina, MD 7 Clinically Relevant Small Animal Model of Therapeutic Hypothermia. Academic Emergency Medicine, 19: 402–408.
My role was as principle investigator
5. Farr CL, Matsushima Y, Lagina* AT 3rd, Luo N, Kaguni LS., et al. (2004). "Physiological and biochemical defects in functional interactions of mitochondrial DNA polymerase and DNA-binding mutants of single-stranded DNA-binding protein." J Biol Chem 279(17): 17047-53. Epub 2004 Jan 30
My role involved experimental design and execution and data analysis
6. Lefai E, Calleja M, Ruiz de Mena I, Lagina AT 3rd, Kaguni LS, Garesse R., et al. (2000). "Overexpression of the catalytic subunit of DNA polymerase gamma results in depletion of mitochondrial DNA in Drosophila melanogaster." Mol Gen Genet 264(1- 2): 37-46.
Experimental design, data acquisition and analysis
7. Lewis DL, Farr CL, Wang Y, Lagina* AT 3rd, Kaguni LS., et al. (1996). "Catalytic subunit of mitochondrial DNA polymerase from Drosophila embryos. Cloning, bacterial overexpression, and biochemical characterization." J Biol Chem 271(38): 23389-94.
Design implementation and data acquisition
8. Lefai E, Calleja M, Ruiz de Mena I, Lagina AT 3rd, Kaguni LS, Garesse R., et al. (2000). "Overexpression of the catalytic subunit of DNA polymerase gamma results in depletion of mitochondrial DNA in Drosophila melanogaster." Mol Gen Genet 264(1- 2): 37-46.
Experimental design, data acquisition and analysis
Published Abstracts
9. A. Lagina, L. Foster, T. Sanderson, R. Kumar, M. Deogracias, R. Tousignant, J. Wider,J. Sullivan. Combination Therapy with IGF-1 and Hypothermia Synergistically Improves Outcome After Transient Global Brain Ischemia in the Rat. American College of Emergency Physicians Scientific Assembly, October, 2010.
10. Lagina AT, Kumar R, Sanderson T, Reed K, Sullivan JM. Small Animal Hypothermia: a more precise model. American College of Emergency Physicians Scientific Assembly, October, 2009.
11. Sullivan JM, Lagina AT, Kumar RF, Wang J. Hypothermia alters protein sumoylation during early reperfusion after focal brain ischemia in the rat. . International Symposium on Cerebral Blood Flow and Metabolism, July 2009.
12. Lagina AT, Kumar R, Sanderson T, Reed K, Sullivan JM. A clinically relevant, precise, and noninvasive model of therapeutic hypothermia in the rat. International Symposium on Cerebral Blood Flow and Metabolism, July 2009.
Other Information
Major Professional Societies
Undersea and Hyperbaric Medical Society
2006-present
Society for Academic Emergency Medicine
2002-present
American College of Emergency Physicians
2002-present
American Academy of Emergency Physicians
2002-present
Wilderness Medical Society
1998-present