Anthony Lagina

Anthony Lagina

Associate Professor

alagina@med.wayne.edu

Anthony Lagina

Office Phone

313-993-2530

Office Location

4201 Saint Antoine Street
UHC - 6G
Detroit, MI 48201

Education

M.D.
Wayne State University
1998-2002

Postgraduate Biochemistry Research Training Program
Michigan State University
1997-1998

B.S. Biochemistry (honors)
Michigan State University
1993-1997
 

Education – Degrees, Licenses, Certifications

M.D., F.A.C.E.P.

Residency

Department of Emergency Medicine
Detroit Receiving Hospital/Wayne State University
2002-2005

Accomplishments

Honors/Awards

Emergency Medicine Basic Research Skills (EMBRS) Workshop EMF Award Recipient
2007

WSU Co-Curricular Outreach Award
2002

Michigan State University Biochemistry Undergraduate of the Year Honorable Mention
1997

Michigan State University Dean’s Student Advisory Committee
1996

National Science Foundation Undergraduate Summer Research Fellow
1995

Professional Experience

Service

Wayne State University School of Medicine

Faculty Advisor for the Wilderness Medicine Student Interest Grou[
2005 - present

Professional

Research Committee Research Forum Member
American College of Emergency Physicians
2012 - present

Medical Operations - Search and Rescue Team
Michigan Technical Rescue Operations Team
2005-2008

Scholarly Service

Academic Emergency Medicine Journal Reviewer
2012-present

ILCOR Review Committee - American Health Association
2014-present

ACEP moderator for scientific assembly poster session
2012-present

Teaching

Wayne State University

Undergraduate Students

Bedside and didactic teaching in the emergency department
2005-present

Mentoring and advising for the wilderness medicine student group
2005-present

Medical Students

Beside and didactic teaching in the emergency department
2005-present

Mentoring and advising for the wilderness medicine student group
2005-present

Residents/Fellows

Bedside and didactic teaching for emergency medicine
2005-present

Teaching at other institutions

University of Michigan

Graduate and Medical Students and Faculty
2011-present

Wilderness medicine topics for didactics sessions and workshops
2011-present

 

Publications

Peer Reviewed Publications

 1. Soar J, Callaway CW , Aibiki M, Böttiger BW, Brooks SC, Deakin CD, Donnino MW, Drajer S, Kloeck W, Morley PT, Morrison LJ, Neumar RW, Nicholson TC , Nolan JP, Okada K, O'Neil BJ, Paiva EF, Parr MJ, Wang TL, Witt J; Advanced Life Support Chapter Collaborators.. (2015) Part 4: Advanced life support: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency cardiovascular Care Science with Treatment Recommendations. Resuscitation. 2015 Oct;95:e71-120. doi: 10.1016/j.resuscitation.2015.07.042.
My role was as review collaborator

2. Soar J, Callaway CW , Aibiki M, Böttiger BW, Brooks SC, Deakin CD, Donnino MW, Drajer S, Kloeck W, Morley PT, Morrison LJ, Neumar RW, Nicholson TC , Nolan JP, Okada K, O'Neil BJ, Paiva EF, Parr MJ, Wang TL, Witt J; Advanced Life Support Chapter Collaborators.. (2015) Part 4: Advanced life support: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency cardiovascular Care Science with Treatment Recommendations. Circulation. 2015 Oct 20;132(16 Suppl 1):S84-145. doi: 10.1161/CIR.0000000000000273.
My role was as review collaborator

3. A. Lagina, L. Foster, T. Sanderson, R. Kumar, M. Deogracias, R. Tousignant, J. Wider, J. Sullivan. Combination Therapy with IGF-1 and Hypothermia Synergistically Improves Outcome After Transient Global Brain Ischemia in the Rat. Academic Emergency Medicine, 2013 Apr; 20(4):344-51
My role was as principle investigator

4. Lagina, A. T., Deogracias*, M., Reed*, K., Bazzi*, D., Chepuri*, R., Foster*, L. and Sullivan, J. M. (2012), The “Refrige-a-RAT-or”: An Accurate, Inexpensive, and Anthony Lagina, MD 7 Clinically Relevant Small Animal Model of Therapeutic Hypothermia. Academic Emergency Medicine, 19: 402–408.
My role was as principle investigator

5. Farr CL, Matsushima Y, Lagina* AT 3rd, Luo N, Kaguni LS., et al. (2004). "Physiological and biochemical defects in functional interactions of mitochondrial DNA polymerase and DNA-binding mutants of single-stranded DNA-binding protein." J Biol Chem 279(17): 17047-53. Epub 2004 Jan 30
My role involved experimental design and execution and data analysis

6. Lefai E, Calleja M, Ruiz de Mena I, Lagina AT 3rd, Kaguni LS, Garesse R., et al. (2000). "Overexpression of the catalytic subunit of DNA polymerase gamma results in depletion of mitochondrial DNA in Drosophila melanogaster." Mol Gen Genet 264(1- 2): 37-46.
Experimental design, data acquisition and analysis

7. Lewis DL, Farr CL, Wang Y, Lagina* AT 3rd, Kaguni LS., et al. (1996). "Catalytic subunit of mitochondrial DNA polymerase from Drosophila embryos. Cloning, bacterial overexpression, and biochemical characterization." J Biol Chem 271(38): 23389-94.
Design implementation and data acquisition

8. Lefai E, Calleja M, Ruiz de Mena I, Lagina AT 3rd, Kaguni LS, Garesse R., et al. (2000). "Overexpression of the catalytic subunit of DNA polymerase gamma results in depletion of mitochondrial DNA in Drosophila melanogaster." Mol Gen Genet 264(1- 2): 37-46.
Experimental design, data acquisition and analysis

Published Abstracts

9. A. Lagina, L. Foster, T. Sanderson, R. Kumar, M. Deogracias, R. Tousignant, J. Wider,J. Sullivan. Combination Therapy with IGF-1 and Hypothermia Synergistically Improves Outcome After Transient Global Brain Ischemia in the Rat. American College of Emergency Physicians Scientific Assembly, October, 2010.

10. Lagina AT, Kumar R, Sanderson T, Reed K, Sullivan JM. Small Animal Hypothermia: a more precise model. American College of Emergency Physicians Scientific Assembly, October, 2009.

11. Sullivan JM, Lagina AT, Kumar RF, Wang J. Hypothermia alters protein sumoylation during early reperfusion after focal brain ischemia in the rat. . International Symposium on Cerebral Blood Flow and Metabolism, July 2009.

12. Lagina AT, Kumar R, Sanderson T, Reed K, Sullivan JM. A clinically relevant, precise, and noninvasive model of therapeutic hypothermia in the rat. International Symposium on Cerebral Blood Flow and Metabolism, July 2009.

 

Other Information

Major Professional Societies
Undersea and Hyperbaric Medical Society
2006-present

Society for Academic Emergency Medicine
2002-present

American College of Emergency Physicians
2002-present

American Academy of Emergency Physicians
2002-present

Wilderness Medical Society
1998-present

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